Medication For Autism and ADHD
Many people with autism have ADHD, and medication for ADHD can sometimes help with the overlapping autism symptoms, such as hyperactivity and an impulsive nature. Some medications can cause adverse effects.
Research is required to better know the effects of co-occurring disorders on treatment outcomes. Drugs like methylphenidate (Ritalin) are typically used to treat ADHD and can help with autism-related symptoms that overlap as well as some anticonvulsant medicines.
Medicines for Inattention
Autism and attention deficit hyperactivity disorder (ADHD) are disorders that can coexist. Between 30 and 50% of people diagnosed with autism also have ADHD symptoms. This co-occurrence is both relevant clinically and epidemiologically, because effective treatment of core symptoms of both disorders improves adaptive functioning and helps prevent negative behavior patterns of coping [1, 2].
Symptoms of ADHD include impulsivity, inattention and hyperactivity. Medications used for the treatment of ADHD generally reduce the symptoms and may help improve academic, social and behavioral outcomes for people with coexisting autism and ADHD.
In an longitudinal study of cohorts, researchers discovered the same percentage of individuals prescribed psychotropic medication regardless of whether they were autistic or not. The class of medication and frequency of prescriptions varied between the two groups. The most frequently used medication was stimulant, followed by atomoxetine and then antipsychotics and SSRIs. In a subgroup analysis, those with ADHD-Combined and with autism were more likely to receive ADHD medications, whereas children with ADHD-Inattentive had a lower chance to be medicated than those with autism in isolation.
Stimulants boost the levels of dopamine, norepinephrine, and other neurotransmitters in your brain that are associated with motivation, reward and decision-making. Stimulant drugs have been proven to be effective in decreasing ADHD symptoms among children with autism and ADHD. However t here are some who may experience side effects like headaches, stomach issues, and insomnia.
Nonstimulant drugs, such as atomoxetine and guanfacine, also seem to reduce ADHD symptoms in people who suffer from autism and ADHD. A few studies suggest that the atypical antipsychotics like aripiprazole and risperidone can reduce irritability in children with ASD. However, further studies are needed to determine whether this is due the reduction of ADHD symptoms or a change in the core ASD behaviors.
Enhanced understanding of co-occurring symptom routes can help clinicians optimize the duration and timing of psychosocial versus pharmacological treatment for each disorder, and to identify the crucial times during which intervention may be more efficient. A better understanding of co-occurring symptom patterns and how they interact over time will assist in identifying the most effective treatment options to counteract the negative effects of ADHD symptoms on ASD essential functions.
Medications for Hyperactivity
Although few research studies have compared psychopharmacological treatment for coexisting ADHD and autism, available data suggests that individuals with both conditions may benefit from optimal use of medication. Numerous clinical studies indicate that stimulant drugs (methylphenidate and atomoxetine) enhance core ADHD symptoms in children and adolescents with ASD.
The same drugs have been shown to be effective in enhancing social skills in individuals with autism. These medications are not risk-free and should only be administered by a physician who is knowledgeable about the risks and benefits of each drug. Furthermore, people with autism react differently to different medications and many medications are dangerous in certain circumstances.

A large-scale study on the population found that two thirds of children ages 6 to 11 and three quarters of adolescents between the ages of 12 and 17 with coexisting ADHD and autism were taking some form of psychotropic medication. This was comparable to the prevalence of psychiatric drug usage among children and teens with ADHD on their own. Comorbid diagnoses such as schizophrenia, intellectual disability and OCD were more common in those who suffer from ADHD and ASD as compared to people with ADHD on their own.
This study also found that individuals with coexisting ADHD and ASD were less likely to start and continue continuous psychopharmacological treatment than those with ADHD alone. The reasons for this are not clear, but it could be due to higher rates of discontinuation in those with ASD due to adverse reactions such as irritability or issues with methylphenidate dosages.
Comorbid ADHD and Autism are associated with more impairments than either condition alone. Therefore it is crucial to optimize the treatment of both conditions. Research should concentrate on identifying psychosocial therapies that work best for coexisting ADHD and autism. These include behavioral therapies, parent training and social skills therapy. They are known to reduce ADHD and autism-related disruptions. Future research should also look at the developmental pathways of co-existing disorders to understand how symptoms change throughout the development process and how this affects treatment. This research will assist in create more specific interventions that are tailored to the needs of people with ADHD and ASD.
Medicines for anxiety
Autism is a multifaceted disorder that affects many different areas including emotions, sleep patterns, concentration, and behavior. While non-medical treatments are usually the most effective first option however, medication can provide relief from certain issues and provide parents and children with new tools to help them succeed in their daily lives. Treatments for ADHD can also offer a significant boost in the ability to deal with certain anxiety and depression that is prevalent among people with autism.
The use of stimulants can be beneficial in treating the "core" ADHD symptoms that affect social and academic progress. A better focus and ability to complete tasks can have a significant effect on writing, reading, and other academic skills. The use of medication can result in a noticeable improvements in the ability to interact with peers and also reduce the frequency of self-injurious behavior, tantrums and aggressiveness may reduce as well.
Antidepressants are often prescribed to decrease irritability in children with autism and improve their mood. These medications include fluoxetine and are also known as selective serotonin reuptake inhibitors (SSRIs). SSRIs are known to be effective in treating anxiety, depression and other ailments among those with autism. However large clinical trials will be required to prove their effectiveness.
Certain antipsychotics like Risperidone and Aripiprazole are used to control the anger, and emotional outbursts, that are common among some individuals with autism. FDA has not yet approved these drugs to treat autism. However, they could be an effective tool for improving emotion regulation in children and adults.
The research is also in progress to determine how co-occurring autism and ADHD affect the trajectory of symptoms over time. A better understanding of these relationships may result in more effective pharmacological and psychological treatments.
It is crucial to be aware that medicines can cause adverse effects and should be used with caution. It is recommended to try other options before beginning treatment with medications, especially in young children. If properly titrated, these medications can be an effective tool to improve the quality of life of those suffering from autism and ADHD.
Medications for Emotions
When a child with autism experiences overwhelming anxiety or depression, the symptoms may be so severe that they cause problems with their daily activities. In these instances, doctors may prescribe medication to help deal with the stress.
The medications for ADHD can be used to reduce anxiety, impulsivity and other signs of autism. These medications are usually utilized in conjunction with other behavioral treatments. Many medications, including SSRIs are able to alleviate anxiety and depression in people with autism. Other medications, like antipsychotics with atypical properties and alpha-2 antagonists, can help reduce irritability among people with autism.
While autism and ADHD are distinct diagnoses, researchers acknowledge that the two disorders frequently occur together. It is estimated that around half of all children who are diagnosed with autism display ADHD symptoms, like hyperactivity and inattention. This is why many families find that they need to use medication to treat both conditions.
Children and adults with ADHD and autism are treated most commonly by taking medication. However, it's not meant to cure autism or eliminate all of the related behaviors. Instead, it can assist in managing specific symptoms that make it difficult to function in school and socially.
Research suggests that atypical antipsychotics like risperidone can help reduce aggression and irritability in people who have autism. They can also reduce the psychotic symptoms, including hallucinations and delusions, which can be experienced by people with autism.
It is important to remember that the majority of the drugs approved by Health Canada have not been specifically studied in children or youth with autism. Instead, they have been approved in a typical manner before being made available for sale with clinical observations in a small number of people with positive outcomes publishing case reports, a rise in off-label use, open-label drug trials and then placebo-controlled controlled, randomized studies.
The most frequently prescribed medications for adolescents and adults with coexisting ASD and ADHD are methylphenidate (Ritalin, Concerta, Metadate) amphetamines (Adderall, Dexedrine, Vyvanse) and the atomoxetine (Strattera). These are also prescribed for children suffering from pure ADHD. Treatments for anxiety, such as SSRIs, benzodiazepines, and anti-seizure medications, have not been thoroughly researched in this group, and the evidence for their effectiveness is not as convincing.